ea0014p559 | (1) | ECE2007
Webb Susan M
, Badia Xavier
, Barahona Maria- Jose
, Colao Annamaria
, Strasburger Christian J
, Tabarin Antoine
, Aken MO van
, Pivonello Rosario
, Stalla Gunther
, Chabre O
, Lamberts Steven WJ
, Glusman Joan E
Chronic exposure to hypercortisolism has a significant impact on patients health and Health-Related Quality of Life (HRQoL), as demonstrated with generic questionnaires. Objective: Develop and validate a disease-generated questionnaire to evaluate HRQoL in patients with Cushings syndrome-CS- (Cushing QoL). Methods: After a literature review, interviews with expert endocrinologists and 10 patients identified HRQoL domains and clinical aspects of the disease; an anal...